@ University of Calgary, Antibe Therapeutics Inc., Canada
Hydrogen sulfide to the rescue: Trials and tribulations of translational research
Ulceration of the gastrointestinal tract by nonsteroidal anti-inflammatory drugs (NSAIDs) remains a major health problem. We have exploited the powerful protective and repair-promoting effects of hydrogen sulfide to design new NSAIDs that are safe in the GI tract. Translating our basic science research to clinical use has been exciting but very challenging.