High thyroid stimulating hormone (TSH) and BRAF mutations are thought to be factors promoting progression of papillary thyroid carcinoma (PTC). However, there is no data about relations between functional profile and BRAF mutation among patients with different morphological features of PTC. In this study we explored the relations between serum TSH, free T3 and T4, morphological characteristics of PTC in both BRAF positive and BRAF negative patients.